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Protein structure modeling

Citation Malmstrom, Lars; Goodlett, David; Protein structure modeling. Methods Mol Biol (2010), 673: 63-72.
Abstract The tertiary structure of proteins can reveal information that is hard to detect in a linear sequence. Knowing the tertiary structure is valuable when generating hypothesis and interpreting data. Unfortunately, the gap between the number of known protein sequences and their associated structures is widening. One way to bridge this gap is to use computer-generated structure models of proteins. Here we present concepts and online resources that can be used to identify structural domains in proteins and to create structure models of those domains.
Synopsis This chapter offers a short overview on how to model protein structures using web-based servers.
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